The re-emergence of XDR & MDR tuberculosis have claimed human life potentially. We here note down details of designing and synthesis of several pyrimido-thiazolyl triazole derivatives and their evaluation against 25 different clinical isolates. “Hit” is identified through this series of compounds which has shown promising activity compared with Isoniazid. The candidate is under further trials for identifying the toxophore and to avoid untoward effects.
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